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Coronary Artery Disease

Norvasc study reports fewer major CV events in coronary artery disease patients

Published in Clinical Trials Week, December 6th, 2004

Pfizer Inc said that patients with coronary artery disease who took its blood pressure lowering medicine Norvasc (amlodipine besylate) had 31% fewer major cardiovascular events compared to patients who received standard care.

The results were published in the current issue of the Journal of the American Medical Association.

In the 2-year Comparison of Amlodipine vs Enalapril to Limit Occurrences of Thrombosis (CAMELOT) trial, 1,997 patients with coronary artery disease and normal or well-controlled hypertension received either Norvasc, the ace-inhibitor enalapril (Vasotec) or placebo to compare the medicines' effectiveness in reducing major...

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