Clinical Trials Week

Acute Maxillary Sinusitis - Five-day telithromycin therapy safe and effective

Anti-Infectives - Probiotics prevent antibiotic-associated diarrhea in infants

Cancer Therapy - Ixabepilone shows promise in phase I clinical trial

Post-Traumatic Stress Disorder - Cognitive therapy significantly ameliorates PTSD symptoms

Respiratory Medicine - Pharmacology of salmeterol delivered by non-CFC inhalers determined

Acute Bacterial Conjunctivitis - Gatifloxacin 0.3% BID safe and effective in clinical trial

Acute Lymphoblastic Leukemia - Company initiates phase I/II clinical trial of talotrexin in patients with ALL

Adenocarcinomas - South Taiwan exhibited increased frequency of bulbomembranous adenocarcinoma

Adverse Drug Reaction - Trials indicate NEXIUM can reduce upper GI symptoms in patients using NSAIDs

Alzheimer Disease - Future test candidates needed for LymPro AD test

Alzheimer Disease - Interrupted vaccine study yields hopeful results

Anemia Therapy - Third course of anti-thymocyte globulin in aplastic anemia studied

Asthma Medicine - Formoterol safe and effective when used as needed

Awards - Stanley Institute awards $3.8 million for developing cognitive deficit therapy

Bladder Cancer - Carcinoma in situ of urinary bladder diagnosed by pirarubicin hydrochloride

Bladder Cancer - Extracapsular extension of pelvic lymph node metastases used as prognosticator

Bladder Cancer - Herceptin may have role in bladder cancer treatment

Bladder Cancer - Patient preferences made integral determinant of bladder cancer treatment

Brain Cancer - Cytopathologic features of atypical teratoid/rhabdoid brain tumor characterized

Breast Cancer - African-American breast cancer deemed the more aggressive phenotype

Breast Cancer - Antibody combined with cancer drug shows promise against breast tumors

Breast Cancer - Chemotherapy regimen associated with life-threatening complications

Breast Cancer - Color-Doppler ultrasound used to evaluate response to neoadjuvant treatment

Breast Cancer - Concurrent use of trastuzumab and chemotherapy significantly reduces recurrence

Breast Cancer - Failed lung cancer drug could help shrink breast tumors

Breast Cancer - Further trial data awaited for Bonefos in the U.S.

Breast Cancer - Prospective study of breast intraoperative ultrasound conducted in 112 patients

Breast Cancer - Studies on HRT use by breast cancer patients can give false hopes

Breast Cancer - Study shows hyperthermia improves effectiveness of radiation therapy

Breast cancer - Breast tumor's biological traits guide hormone therapy

Business & Finance - Biopharmaceutical company reports loss of $0.09 per share

Business & Finance - Pharmaceutical company records loss of $0.12 per share, reports on ALS drug

Business & Finance - Pharmaceutical company reports first quarter 2005 operating results

Business & Finance - Pharmaceutical executives discuss funding, clinical trials in shareholder letter

Business & Finance - Pharmaceutical firm reports loss of $0.05 per share, clinical trial update

Business & Finance - S&P report gives company 'bullish' rating for Alzheimer urine test, others

Business Update - Company achieves $35 million in milestones from GSK

Business Update - Swiss peptide manufacturing company expands manufacturing capacity

Cancer Therapy - Cancer therapeutics development company refocusing resources

Cancer Therapy - Phase II trial of AP23573 initiated in hormone-refractory prostate cancer

Cancer Therapy - Phase II trial of Adh-1 to examine eight tumor types that express N-cadherin

Cardioprotection - Review explains concepts of hypothermia-associated neuro- and cardioprotection

Cardiopulmonary Bypass - Nitric oxide gas and iloprost reduces platelet dysfunction during CPB

Cardiovascular Disease - Trial using noninvasive cardiovascular risk assessment technology announced

Cardiovascular Research - Study compared influences of antianginal drugs on CV response to orthostasis

Cervical Cancer - Data presented on vaccine response in adolescents

Chemotherapy - Chemoradiation with and without surgery for esophageal squamous cell carcinoma

Chemotherapy - Early responses to chemotherapy of hematologic cells prognosticated child ALL

Chemotherapy - Gemcitabine and capecitabine combined in patients with advanced biliary cancer

Cisplatin - Radiotherapy, brachytherapy, and cisplatin chemotherapy treated cervical cancer

Clinical Trials - Biopharmaceutical product developer reports first quarter 2005 financial results

Clinical Trials - Phase 2 monotherapy trial of oral entry inhibitor HIV drug initiated

Collaborations - Pharma companies enter into research agreement on antibody product

Collaborations - Swiss companies sign agreement to produce drug to treat pulmonary disease

Colon Cancer - Adjuvant treatments for colorectal cancer compared

Colon Cancer - Aspirin use may protect against colon cancer recurrence, reduce risk of death

Colon Cancer - Family history associated with incidence of colorectal cancer

Colon Cancer - Keyhole surgery to become gold standard for colon cancer treatment

Colon Cancer - One-stage resection compared to anastomosis of colon obstruction

Colon Cancer - Outcomes of emergency and elective surgeries for colon cancer examined

Colorectal Cancer - Attitude differences between patients seen in willingness to join in drug trials

Colorectal Cancer - Colorectal papillomavirus infection implicated in colorectal cancer

Colorectal Cancer - High-powered endoscopic diode laser therapy palliated colorectal cancer patients

Contraception - Treatment phase of EASE transcervical sterilization trial completed

Coronary Artery Disease - Intensive atorvastatin is not more beneficial than diet and low-dose lovastatin

Coronary Artery Disease - Weekly azithromycin did not alter risk of cardiac events

Deep Vein Thrombosis - Company provides update on FIBRIMAGE development program

Diabetes Therapy - Cerivastatin increases forearm vascular responses in diabetic men

Diabetes Therapy - Glucosidase inhibitor effects on hyperglycemia linked to symptoms

Diagnostics - Computed tomography accurately guided core needle biopsy of tumors

Diet & Nutrition - High-dosage vitamin E supplements should be avoided

Diet & Nutrition - Novel therapeutic for hyperparathyroidism discovered

Down Syndrome - Contract signed to begin human clinical studies of prenatal DNA tests

Drug Development - Astelin provides greater improvement relieving allergy symptoms than Zyrtec

Drug Development - Favorable results reported from Aurexis phase II trial for Staph infections

Drug Development - Mouse model proposed for preclinical testing of vaginal microbicides

Drug Development - Phase II results of psoriasis drug presented at dermatology meeting

Drug Development - Phase IIB malaria trial commences

Drug Development - Phase III results presented for Mepact in osteosarcoma

Drug Development - Positive Aggrastat injection strategy trial data published

Drug Development - Positive phase II results reported for anti-obesity compound

Drug Development - Protein-focused company advances anti-cancer compounds to pre-clinical studies

Drug Development - Scottish Medicines Consortium accepts therapy for heart failure in LVSD patients

Drug Research - Oral absorption improves with levovirin prodrug

Eczema - Preclinical data positive for NF-kB Decoy drug candidate

Embolism - Clinical outcome of patients with venous thromboembolism transcribed

Endocrinology - DHEA replacement benefits young women with panhypopituitarism

Endocrinology - Glucose transporter-1 expressed in urothelial papilloma of the bladder

Endometrial Cancer - Benefits of laparoscopy compared with laparotomy in endometrial cancer patients

Finance - Antoimmune-focused pharmaceutical company reports first quarter 2005 results

Finance - Biopharmaceutical company reports first quarter 2005 financial results

Finance - Biotechnology company focused on CNS therapies reports financial results

Finance - CORLUX maker reports net loss for first quarter

Finance - Cancer-focused pharmaceutical company reports first quarter 2005 results

Finance - Cross Country Healthcare reports revenue of revenue of $158M for Q1

Finance - Drug-delivery company announces first-quarter 2005 financial results

Finance - Drug-delivery company reports $5.4M Q1 net loss, updates development programs

Finance - Gastro-focused pharmaceutical company reports first quarter 2005 results

Finance - Genomics company announces $27.4 million net loss for first quarter