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Breast Cancer

Chemotherapy regimen associated with life-threatening complications

Published in Clinical Trials Week, June 6th, 2005

The chemotherapy regimen of doxorubicin plus docetaxel, used to treat breast cancer in a clinical trial, was associated with an increased risk of serious complications, resulting in the premature termination of the trial, according to a study in the May 18, 2005, issue of the Journal of the American Medical Association.

Combinations of certain breast cancer drug classes have proven superior to some single classes alone in advanced or metastatic breast cancer, according to background information in the article. Uncertainties remain regarding the optimal schedule of administration of combination regimens, as well as safety and cost issues, and whether some drugs...

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