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Acute Vertebrobasilar Occlusion

IV Abciximab, intra-arterial rtPA, and additional PTA/stenting improve outcome

Published in Clinical Trials Week, July 18th, 2005

A combination of intravenous (IV) Abciximab, intra-arterial recombinant tissue plasminogen activator (rtPA), and additional percutaneous transluminal angioplasty (PTA)/stenting appears to improve clinical outcome in acute vertebrobasilar occlusion.

"A combined therapy of local recombinant tissue plasminogen activator fibrinolysis and intravenous Abciximab platelet inhibition with additional percutaneous transluminal angioplasty/stenting may improve recanalization and neurological outcome in patients with acute vertebrobasilar occlusion. Combined FAST therapy consisted of intravenous bolus of Abciximab (0.25 mg/kg) followed by a 12-hour infusion therapy (0.125 mcg/kg per...

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