Published in Clinical Trials Week, September 5th, 2005
"COMP is a noncollagenous protein, a glycoprotein, the function of which is to bind to type II collagen fibers and stabilize the collagen fiber network in the articular cartilage. In the serum of the normal population the COMP level is 5 mcg/ml.
"An increased level of COMP in the synovial fluid was described in the early stage of RA, whereas in advanced stages of RA, the level of COMP decreased. In this study we assessed the serum COMP level in patients with RA and knee OA and found a correlation between the...
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