Depression Treatments

Clinical trials reveal sex differences in antidepressant response

Published in Clinical Trials Week, September 5th, 2005

Clinical trials have revealed possible sex differences in antidepressant response.

"Some previous reports suggest that women respond differently than men to antidepressant treatment," scientists in the United States observed. "Much of this literature compares men and women's response to tricyclics to that of newer antidepressants (SSRIs, SNRI), or only examines one particular antidepressant."

"This study compares men and women's responses to 6 newer antidepressants," wrote A. Khan and colleagues. "A total of 15 randomized, placebo-controlled trials that included 323 depressed patients were examined for sex differences in antidepressant treatment...

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Source: Clinical Trials Week (2005-09-05)

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