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Crohn Disease

Phase II Trial results for treatment of Crohn Disease with Cimzia are positive

Published in Clinical Trials Week, November 14th, 2005

A single 400 mg injection of Cimzia (certolizumab pegol, CDP 870) every 4 weeks was effective in maintaining control of the signs and symptoms of Crohn disease following induction therapy, according to pivotal phase III research presented recently at the annual meeting of the American College of Gastroenterology.

The study, entitled PRECiSE 2, found that a significantly higher proportion of patients who responded to an induction regimen of 400 mg Cimzia(tm) at weeks zero, two and six, were able to maintain clinical response and achieve remission by week 26 when given a single injection every 4 weeks, compared to those treated with placebo. A regulatory submission for...

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