Clinical Trials Week

Clinical Trials - Olanzapine has greater efficacy but more side effects than ziprasidone

Clinical Trials - Once weekly dalbavancin as effective as twice daily linezolid for complicated SSSIs

Drug Development - Enrollment completed in phase III study of Entereg in postoperative ileus

Urology - Intradetrusor botulinum toxin B effective for patients with adverse reactions to toxin A

Actinic Keratosis - Phase IIa trial results show PEP005 gel effective on precancerous skin condition

Allergy & Immunology - Olopatadine eyedrop treatment ameliorate ocular symptoms in most patients

Bladder Cancer - Urine telomerase activity levels used to diagnose bladder cancer

Breast Cancer - Alliance to study use of magnetic resonance focused ultrasound to eliminate breast tumors

Breast Cancer - Company announces phase II data on E7389, a new therapy for the treatment of breast cancer

Breast Cancer - Delivery of radiotherapy in the DBCG 82 b&c trials analyzed

Diabetes Therapy - Research add new data to diabetes therapy body of knowledge

Breast Cancer - Dose-dense chemotherapy for early breast cancer was found to be safe, similar to standard regimen

Breast Cancer - Non-uniform classification practices in breast cancer resulted in distorted statistics

Breast Cancer - Revision of the T4 category of breast cancer needed

Breast Cancer - Study shows superior response rate of Abraxane in women with metastatic breast cancer

Breast Cancer Vaccine - HER2/neu vaccine prevents recurrence in high-risk breast cancer patients

Business & Finance - Proposed acquisition of Cita NeuroPharmaceuticals announced

Cancer Research - Study of paclitaxel-based chemo/radiation therapy for LANSCLC finds long-term survival regimen

Cancer Therapy - Administration of dexrazoxane during treatment with doxorubicin resulted in less cardiotoxicity

Cancer Therapy - Gemcitabine and irinotecan treated patients with carcinoma of an unknown primary site

Cancer Therapy - Inerleukin-12 plus interferon reported to be safe as an experimental therapy for some cancers

Cancer Therapy - U.S. FDA accepts IND application for ENMD-1198

Cancer Therapy - U.S. FDA grants IND clearance for eniluracil

Cardiology - Cilostazol therapy increased luminal diameter and lowered restenosis rate

Cardiovascular Research - Patient enrollment complete in study of bioabsorbable collagen matrix technology

Cervical Cancer - FDG-PET used to detect metastases of uterine cervical cancer when surgical staging is inappropriate

Cervical Cancer - Researchers suggest FIGO guidelines be reassessed to better reflect clinical practice

Chronic Hepatitis Infections - Paraoxonase-1 polymorphisms are associated with chronic HCV infection

Clinical Trials - Agreement reached with U.S. FDA on statistical analysis plan for anxiety drug

Clinical Trials - Antiviral activity shown in one of two antibodies comprising hepatitis C drug candidate

Clinical Trials - Bronchitol dose finding study for cystic fibrosis commences

Clinical Trials - Company expands monoclonal antibody SGN-40 program into chronic lymphocytic leukemia

Clinical Trials - Enrollment complete in phase I clinical trial of SB-509 for diabetic neuropathy

Clinical Trials - Enrollment complete in trial of beta-estradiol eluting stent system

Clinical Trials - Enrollment completed ahead of schedule in phase II trial of ozarelix for BPH

Clinical Trials - First patient completes treatment in phase I of Provecta trial

Clinical Trials - INNO-105 clinical trial initiated for treatment of advanced solid malignancies

Clinical Trials - Jacob P. Lalezari, MD, at Quest Clinical to lead next trial of new immunotherapy

Clinical Trials - New research company to help address chronically under-represented minorities in clinical trials

Clinical Trials - Pharma development company completes phase II study of low estrogen contraceptive patch

Clinical Trials - Phase II trial to evaluate synthetic epothilone for cancer treatment

Clinical Trials - Study finds xyrem relieves pain, improves function in fibromyalgia patients

Clinical Trials - Study shows improved FEV(1) in pediatric asthma patients treated with HFA inhaler

Clinical Trials - U.S. FDA gives approval for full expansion of COSTAR II drug-eluting stent trial

Colon Cancer - Hartmann reversal associated with more complications than loop ileostomy reversal

Colon Cancer - Women and the elderly with stage III colon cancer should also receive chemotherapy, say researchers

Complementary & Alternative Medicine - Green tea polyphenols did not affect glucose levels or insulin resistance

Complementary & Alternative Medicine - Study cites use of glucosamine, chondroitin combination as being effective for joint health

Diabetes Complications - V.A.C. Therapy shown effective and safe for healing diabetic foot amputation wounds

Diabetes Therapy - Findings describe new data in diabetes therapy research

Diabetic Nephropathy - Researchers detail new studies and findings in the area of diabetic nephropathy

Diagnostics - Basic fibroblast growth factor reflects renal cell cancer invasion and metastasis

Diagnostics - Data support the potential of breast-specific gamma imaging in reducing benign biopsies

Diagnostics - Real-time PCR improves diagnostic yield, but raises treatment costs

Diet & Nutrition - Consumption of cruciferous vegetables could prevent lung cancer

Diet & Nutrition - Diet with oat beta-glucans improved lipid and glucose metabolism, barley beta-glucans did not

Diet & Nutrition - Low-allergen maternal diet reduced distressed behavior among breastfed infants with colic

Diet & Nutrition - Role of diet and nutrition in cervical carcinogenesis discussed

Disease Associations - Poorer quality of life in breast cancer survivors might be related to untreated symptom cluster

Drug Delivery - Separate intravenous access recommended for fat emulsion infusion in neonates

Drug Development - ACP-103 reduced haloperidol-induced akathisia in phase II trial of patients with schizophrenia

Drug Development - Alzheimer disease patients demonstrate statistically significant benefits with Phenserine

Drug Development - Bermuda-based firm completes acquisition of exclusive worldwide rights to Xerecept

Drug Development - Dosing of first multiple dose cohort of AEOL 10150 in ALS patients completed for phase I trial

Drug Development - ERK protein activation assists in adipocyte maturation and regulation of lipid blood level

Drug Development - FR177391 is promising treatment option for management of hypertriglyceridemia

Drug Development - Health Canada issues notice of non-compliance for Marqibo

Drug Development - New drug application submitted to U.S. FDA for once-daily analgesic tramadol

Drug Development - Patient enrollment completed in phase III trial for CellCept in myasthenia gravis

Drug Development - Phase I/II trial initiated for bone formation therapy in the spine