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Once weekly dalbavancin as effective as twice daily linezolid for complicated SSSIs

Published in Clinical Trials Week, December 26th, 2005

Once weekly treatment with dalbavancin is as effective as twice daily linezolid treatment for patients with complicated skin and skin structure infections (SSSIs).

"Dalbavancin, a novel lipoglycopeptide with a pharmacokinetic profile that allows weekly dosing, is active against Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA)," scientists in Pennsylvania explained. The efficacy of dalbavancin for SSSI treatment was previously "demonstrated in a phase 2 study."

"In a phase 3 noninferiority study," conducted by L.E. Jauregui and colleagues working at Vicuron Pharmaceuticals, "patients with complicated SSSIs,...

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