Clinical Trials Week

Biliary Tract Carcinoma - Biliary tract carcinoma treated by chemoradiation

Cystic Fibrosis - Inhaled hypertonic saline is safe and effective additional therapy for cystic fibrosis patients

Emergency Medicine - Electronic link between emergency and family physicians does not lower resource use

Mental Health - Treatment-resistant depression responds to sequential bilateral rTMS

Adenomas - DNA methylation patterns of adenomas studied

Aggressive Behavior - Characterization of aggressive behavior influences the success of pharmacological treatment

Alzheimer Disease - Cerebrolysin was well tolerated and demonstrated improved cognition in Alzheimer patients

Anemia - Health Canada authorizes ProMetic BioSciences to begin Ib/II trial of PBI-1402 for anemia

Angina - Update on GENASIS trial announced by Corautus Genetics

Asthma - Dosing of first patient in trial of IV zileuton completed by Critical Therapeutics

Autism - PediaMed completes clinical trial enrollment to study GI dysfunction in children with autism

Avian Influenza - Avian influenza vaccine well tolerated in patients

Avian Influenza - Positive pre-IND meeting with U.S. FDA for avian flu vaccine completed by Generex

Benign Prostatic Hyperplasia - BXL628 arrests prostate growth in patients with benign prostatic hyperplasia

Benign Prostatic Hyperplasia - QLT trial of lemuteporfin-injectable did not meet primary efficacy objective at 3 months

Bipolar Disorder - Functional polymorphisms are associated with bipolar disorder

Blood Pressure - Blood pressure response to 17beta-estradiol varies according to age

Blood Pressure - Pyridostigmine alone or with midodrine may improve standing blood pressure

Breast Cancer - Elderly patients with metastatic breast cancer should be included in prospective trials

Breast Cancer - M. D. Anderson Cancer Center to investigate chemokine antagonist for breast cancer

Breast Cancer - Roche pursues European market approval of Herceptin for early-stage HER2-positive breast cancer

Business & Finance - BioMS Medical records loss of $0.46 per share

Business & Finance - Cadence Pharmaceuticals acquires second phase III product, $60.8M financing

Business & Finance - Coley Pharmaceutical Group reports Q4 revenue of $5.4 million

Business & Finance - Fourth-quarter 2005 results reported by Cepheid; total revenues increase 16%

Cancer Therapy - Advaxis' listeria cancer vaccine receives regulatory approval for phase I/II testing

Cancer Therapy - Aegera initiates third trial for AEG35156 for patients with acute myeloid leukemia

Cancer Therapy - Antimetastasis data to be presented by Chemokine at meeting

Cancer Therapy - Brain cancer patients living longer after DCVax-Brain personalized vaccine therapy

Cancer Therapy - Multikine treatment increases survival in head and neck cancer patients

Cancer Treatments - ProStrakan receives U.S. FDA approval of IND for patch to treat side effects of chemotherapy

Cancer Vaccine - Contract arrangement announced for cGMP production of GRNVAC1 for clinical trials

Cancer Vaccine - Vaccine induces response against carcinoembryonic antigen in patients with metastases

Cardiac Cell Therapy - Enrollment in phase II trial of cardiac cell therapy ended by Genzyme

Cardiology - New clinical data shows antisense drug Isis 301012 significantly reduces triglycerides

Central Nervous System - Memory Pharmaceuticals announces positive preliminary phase I cognitive data for MEM 3454

Cervical Cancer Vaccine - Human papillomavirus-16 vaccine prevents cervical intraepithelial neoplasia

Cirrhosis - Recurrence of hepatocellular carcinoma after liver resection evaluated

Clinical Trials - Approval for human trials on new rotary VAD feasibility granted by Greek health ministry

Clinical Trials - Celsion signs Agreement with Fast Track Systems and CROCAS PBT

Clinical Trials - Clinical study of small molecule Telintra tablet for myelodysplastic syndrome initiated

Clinical Trials - Enrollment in phase 1 trials for anti-inflammatory therapeutic begun

Clinical Trials - Final trial results show intranasal morphine for post-surgical pain meets endpoints

Clinical Trials - First patient enrolled in phase 2 sinus lift study of bone augmentation product

Clinical Trials - Norwood Abbey commences phase II trial of Lupron Depot in autologous bone marrow transplants

Clinical Trials - Positive results reported from phase 3 trials of desonide topical steroid in aqueous gel

Colon Cancer - Clinical trial Buddy Program offered by Colon Cancer Alliance

Colon Surgery - Gum-chewing may speed recovery after colon surgery

Colorectal Adenocarcinomas - Molecular features of signet ring cell cancer and mucinous cancer compared

Colorectal Cancer - Clinical utility of standardized uptake value on FDG-PET in colorectal cancer assessed

Colorectal Cancer - Colorectal cancer linked to aberrant promoter methylation of multiple genes

Colorectal Cancer - Colorectal cancer patients preferred oral to intravenous therapy

Colorectal Cancer - Link between polymorphisms and environmental factors in colorectal cancer risk discussed

Complementary & Alternative Medicine -  Citrus aurantium reviewed as alternate overweight and obesity treatment

Complementary & Alternative Medicine - Acupuncture for stroke rehabilitation ineffective

Coronary Artery Bypass - Coronary artery bypass outcomes may be improved with thoracic artery skeletonization study

Dental Care - Use of an atomizer improved pediatric dental patient receptivity to intranasal midazolam

Depression - Men with symptoms of depression were more likely to be offered treatment

Diabetes - Cortisol synthesis inhibitor taken into phase II clinical trial by DiObex

Diabetes Control - OSI Pharmaceuticals initiates phase IIa trial for glycogen phosphorylase inhibitor, PSN357

Diabetes Therapy - Reports add new data to diabetes therapy research

Diagnostics - Researchers provide details of new studies and findings in the area of diagnostics

Diet & Nutrition - Does folic acid and vitamins B₆ and B₁₂ reduce the risk of major CV events?

Diet & Nutrition - Vitamin C supplementation might reduce frequency of common cold

Drug Delivery - CoStar drug-eluting stent gets CE Mark

Drug Development - Access Pharmaceuticals initiates a new AP5346 study in patients with head and neck cancer

Drug Development - Advanced Magnetics panel recommends continuation of ferumoxytol phase III trial

Drug Development - Allergy Therapeutics commences sublingual allergy vaccine trial

Drug Development - Arixtra shown to reduce risk of venous thromboembolism in acutely ill patients

Drug Development - AstraZeneca withdraws Exanta from the market, terminates development

Drug Development - BioSante Pharmaceuticals submits Bio-E-Gel new drug application to U.S. FDA

Drug Development - BioVex begins dosing of patients in phase II trial of OncoVEXGMCSF

Drug Development - Biomarker discovery program initiated to streamline drug development for tuberculosis

Drug Development - Biota commences phase I trial of common cold drug candidate

Drug Development - Biovest submits amendment request to U.S. FDA for BiovaxID personalized anticancer vaccine

Drug Development - CytRx enrolls first patient in phase IIA trial of arimoclomol for ALS

Drug Development - Cytochroma granted U.S. FDA approval to commence phase II trial of psoriasis treatment

Drug Development - Hepatitis drug data presented at meeting

Drug Development - InSite Vision to present results from phase III trial of AzaSite for eye infections

Drug Development - Itopride does not meet primary endpoint in phase III trial

Drug Development - Oral iclaprim shown to achieve results comparable to intravenous administration