Rectal Cancer

Rectal cancer treated by adjuvant chemotherapy with folinic acid and 5-fluorouracil

Published in Clinical Trials Week, September 25th, 2006

Adjuvant chemotherapy with folinic acid (FA) and 5-fluorouracil (5-FU) was effective in the majority of rectal cancer patients previously treated by preoperative radiochemotherapy (RCT) and curative tumor resection.

"The role of postoperative adjuvant chemotherapy in patients with rectal cancer pretreated by preoperative RCT and curative surgery is still poorly investigated. We pooled data from both arms of a phase III trial in which patients with locally advanced (T3/4) rectal cancer were randomized to preoperative RCT alone or combined with pelvic radio-frequency hyperthermia," scientists in Germany reported.

"After surgery, R0-resected patients...

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Source: Clinical Trials Week (2006-09-25)

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