Susan Hasty, Publisher
Table of Contents . . . October 16th, 2006
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Clinical Trials Week | Other Publications
Cardiology - Women with atrial fibrillation were more prone to anticoagulant-related bleeding than men
Clinical Trials - Recurrence prevention in lone paroxysmal atrial fibrillation is better with amiodarone combinations
Diabetes Therapy - Rosiglitazone is effective and well tolerated in therapeutic regimens in type 2 diabetes
Allergy & Immunology - Cytos Biotechnology's CYT003-QbG10 achieves efficacy in phase IIa pilot study
Alzheimer Disease - Medivation reports phase 2 trial of Alzheimer drug meets all five efficacy endpoints
Alzheimer Disease - Roskamp Institute announces launch of clinical study on Alzheimer treatment
Angiology - Inhibition of thrombin generation is reversed by a recombinant factor
Angiology - Recurrent venous thromboembolism is associated with polymorphism homozygosity
Antibacterial Agents - Chlorhexidine-impregnated dressing reduces vascular and epidural catheter colonization
Antifungal Therapy - Published study finds Candida albicans rapid diagnostic text saves on antifungal therapy costs
Asthma - Study shows MP3 players useful in getting asthma management information to adolescents
Atherosclerosis - Coronary disease markers are unaffected by modest dosing of renin-angiotensin system inhibition
Avian Influenza Vaccine - sanofi pasteur generates first clinical trial lot of cell-based H7N1 vaccine for bird flu
Basal Cell Cancer - Basal cell carcinoma of the nasolabial fold required more complex surgery
Benign Prostatic Hyperplasia - Nymox announces positive results from benign prostatic hyperplasia trial
Blood Disorders - New once-daily oral iron chelator treats iron overload
Bone Disease - Amgen presents data on denosumab and sclerostin
Breast Cancer - Breast cancer patients may benefit from individual psychosocial support
Breast Cancer - Breast cancer patients with non-negative margins may be treated with radiotherapy
Breast Cancer - Breast cancer prognosis determined by stage at diagnosis
Breast Cancer - New-onset breast discomfort may be related to increased mammographic density
Business & Finance - Palatin Technologies reports fiscal year end 2006 results
Business Update - Alquest launches medical device-focused clinical trial service in India
Business Update - Opexa begins Phase IIb multiple sclerosis study; reports positive Phase I/II data
Business Update - Poniard Pharmaceuticals expands picoplatin agreement
Business Update - Siemens develops scalable method to transfer data from medical record to data capture system
Cancer Incidence - Increased cancer incidence not associated with fluvastatin treatment
Cancer Research - Researchers report Peregrine's phospholipid-targeted antibodies reduce tumor growth in animals
Cancer Therapy - Hana provides Talvesta (talotrexin) for Injection update
Cancer Therapy - Oral squamous cell carcinoma patient response to intra-arterial chemotherapy reduced by granisetron
Cardiology - Cardiac resynchronization therapy for heart failure reduces mortality
Cardiology - Myocardial infarction genetic risk assessed
Cardiology - Pediatric heart failure is beneficially treated using nesiritide
Cardiovascular Disease - Circadian rhythms are important in drug response in hypertension and coronary heart disease
Cardiovascular Disease - Evidence-based use of levosimendan is reviewed in different clinical settings
Celiac Disease - Alba initiates phase II trial for Zonulin antagonist AT-1001 for autoimmune disorder
Cerebellar Ataxia - Cerebellar ataxias may be differentiated by cerebrospinal fluid analysis
Cervical Cancer - Cervical cancer oxygen tension inversely correlates with circulating endothelial progenitor cells
Chronic Idiopathic Constipation - Sucampo's Amitiza effective in treating constipation in people age 65 and older
Clinical Trials - Acorda announces positive Phase III Fampridine-SR study in people with multiple sclerosis
Clinical Trials - Acrux to start U.S. trial of its testosterone lotion for men
Clinical Trials - Angiographic isthmus evaluation may predict efficacy of RF catheters and risk of crossover
Clinical Trials - Cardioprotective effects of sevoflurane were not supported
Collaborations - ACRS and WebbWrites announce strategic alliance
Critical Care Medicine - Severely injured patients examined for toll-like receptor expression
Crohn Disease - Avidia initiates trial of inhibitor of interleukin-6 for Crohn disease
Dental Research - Dental implants with a natural taper design are assessed in clinical practice
Dermatology - NUCRYST Pharmaceuticals announces preliminary results of Phase II dermatology study
Diabetes & Erectile Function - In men with type 1 diabetes, vardenafil significantly improves erectile function
Diabetes Prevention - GlaxoSmithKline's Avandia reduced risk of progression from pre-diabetes to type 2 diabetes
Diabetic Neuropathy - Sangamo presents positive results on DNA-binding protein therapy in diabetic neuropathy
Drug Development - Acceleron Pharma presents positive ACE-011 preclinical data
Drug Development - CepTor executes Letter of Intent with Ferring for late-stage product targeted for Phase 2B trials
Drug Development - Critical Therapeutics announces results of CTI-01 Phase II trial
Drug Development - Prometic expands sites for PBI-1402 trials for anemia
Finance - Array BioPharma receives phase II milestone payment from AstraZeneca
Gastric Cancer - Gastric intestinal metaplasia's link to COX-2 inhibitors requires further investigation
Gastroenterology - Progenics, Wyeth start Phase III clinical program of intravenous methylnaltrexone for post-op ileus
Gaucher Disease - Positive results in studies on mechanism of Amicus' treatment for Gaucher disease published
Genetics & Genomics - A novel trinucleotide repeat expansion identified
HIV/AIDS HAART - Simplified maintenance therapy with atazanavir-ritonavir maintains virologic suppression
Hemodialysis - Positive preclinical data released on Vascular Wrap
Hepatitis A Virus - Hepatitis A virus-Helicobacter pylori association documented
Hepatitis B Virus - Chronic hepatitis B core promoter mutations associated with viral breakthrough
Hepatitis C Therapy - Peregrine's antiphospholipid platform broadened by newly validated anticancer target
Hepatitis C Virus - Chronic hepatitis C risk of hepatocellular carcinoma is related to a promoter
Hypertension - BioMarin completes enrollment of phase II study of 6R-BH4
Imaging - Nasopharyngeal carcinoma detected by F-18-fluoro-2-deoxy-D-glucose positron emission tomography
Intraocular Pressure - pSivida begins phase II clinical study of Mifepristone ophthalmic product
Kidney Disease - Implantable cardioverter defibrillator recipients with renal insufficiency have high mortality
Liver Cancer - BioAlliance reports final results of its doxorubicin Transdrug phase I/II trial for liver cancer
Lung Cancer - Gene mutation in lung cancer patients outpaces copy number for predicting gefitinib sensitivity
Lung Cancer - Lung cancer patients selected for resection by Xe-133-radiospirometry
Lung Cancer - OSI Pharmaceuticals launches study of Tarceva as adjuvant treatment for non-small cell lung cancer
Lymphoma - Pharmion initiates Phase II clinical trial in B-cell lymphoma
Market Analysis - Report examines the issues and concerns about translational medicine, how they can be addressed
Medical Devices - NuVasive treats first patient with NeoDisc cervical disc replacement
Melanoma - Dr. Steven O'Day announces positive results in multicenter trial of new agent against melanoma
Melanoma - SciClone, Sigma-Tau present encouraging interim data on malignant melanoma response trial
Mental Health - Survey to compare women with/without borderline personality disorder was evaluated
Mental Health - Traumatic brain injury patients may benefit from creatine administration
Mergers & Acquisitions - INC Research acquires Pharmaceutical Resource Corp.
Myeloid Leukemia - Initial patients treated in multinational phase II/III study of ChemGenex's Ceflatonin
Neuropathic Pain - Pfizer's Lyrica approved in Europe for difficult-to-treat nerve pain
Non-Small Cell Lung Cancer - Talabostat non-small cell lung cancer trial presented at gene therapy of cancer conference
Nonmelanoma Skin Cancer - Nonmelanoma skin cancer prophylaxis accomplished via facial resurfacing
Obesity Therapy - OREXIGEN reports positive 24-week results for Contrave phase III obesity treatment study
Obstetrics - Pregnant women respond favorably to uterine artery ligation treatment for uterine fibroids
Ophthalmology - An egg a day helps promote eye health
Orthopedics - Aastrom Biosciences reports interim data from phase I/II trial of tissue repair cells
Pancreatic Cancer - An in vivo platform is needed for optimal translational drug development in pancreatic cancer
Paroxysmal Nocturnal Hemoglobinuria - Alexion submits biologics license application for Soliris to treat blood disorder
Paroxysmal Nocturnal Hemoglobinuria - Monoclonal antibody drug eculizumab improves PHN hemolytic anemia symptoms, study shows
Patents - Ortec obtains second U.S. patent allowance on haptide cell attachment technology
Pediatric Cancer - Pediatric cancer patients commonly administered psychotropic medication
Pediatrics Otorhinolaryngology - Adenotonsillectomy effect on serum immunoglobulin levels in children is assessed
Personnel - Immune Response Corporation adds James L. Foght, PhD, to board of directors
Prostate Cancer - Antisoma presents positive data from AS1404 phase II trial in prostate cancer
Prostate Cancer - Prostate cancer detected by DNA integrity assay
Prostate Cancer - Prostate cancer patients responded to higher dose of docetaxel
Prostate Cancer - Prostate cancer prevention strategies should target individual's specific risk factors
Sexual & Reproductive Health - Ovarian size may be related to risk of tumor development in postmenopausal women
Sexual & Reproductive Health - Position on use of hormone therapy in Latin America women has been released by expert panel
Statins - Statin therapy pleiotropic effects extend their use to intensive care units
Statins - Statins for treating inflammation in acute coronary syndromes are focus of review
Surgical Technology - Gastric cancer treated by high segmental gastrectomy
Surgical Technology - The ProDisc-L artificial disc proved superior to spinal fusion
Type 2 Diabetes - NovoMix 30 insulin is alternative to basal-bolus therapy for Type 2 diabetes
Vaccine Efficacy - Probiotics improve vaccine antibody responses to Hib vaccine in allergy-prone infants
Virology - Researchers are investigating whether reovirus can be used to treat malignant glioma
Asthma - Recent findings in asthma described by researchers from South Korea, Japan and Italy
Brain Cancer - New findings from the United States and Spain in the area of brain cancer detailed
Brain Cancer - Recent findings in brain cancer described by researchers from the United States, Austria and South Korea
Breast Cancer - Findings from the United Kingdom in breast cancer provide new insights
Breast Cancer - New findings in breast cancer described from U, the United States and Brazil
Breast Cancer - Research from Italy and Netherlands add new data to breast cancer body of knowledge
Breast Cancer - Research from the United States and Taiwan in breast cancer provides new insights
Breast Cancer - Researchers' work from France, the United Kingdom and the United States adds to breast cancer body of knowledge
Cancer Treatment - Researchers from Australia and the United States provide details of new studies and findings in the area of cancer treatment
Cardiology - New findings from the United States, Germany and Canada in the area of cardiology described
Cervical Cancer - Studies from the United States, Italy and United Kingdom advance knowledge in cervical cancer research
Clinical Trials - Studies from the United States and Italy describe new findings in clinical trials research
Colorectal Cancer - Researchers from Scotland, Italy and the South Korea publish new studies and findings in the area of colorectal cancer
Depression - Recent findings from the United States and Italy illuminate research in depression
Depression - Recent studies from the United States and Argentina add new data to depression research
Diabetes - New findings from Japan, Austria and the United States in the area of diabetes detailed
Diabetes - Reports from Germany and the United States advance knowledge in diabetes research
Gastric Cancer - Reports from Japan add new data to gastric cancer research
HIV/AIDS - Studies from the United States and Spain describe new findings in HIV/AIDS research
Heart Disease - New research from the United States, France and Scotland in the area of heart disease detailed
Hepatitis C Virus - Findings from Brazil, the United States and Spain advance knowledge in hepatitis C virus research
Hepatitis C Virus - New research from Greece, the United States and India in the area of hepatitis C virus detailed
Hepatitis C Virus - Reports from Germany, Japan and Sweden add new data to hepatitis C virus research
Hepatitis C Virus - Reports from the United States and Denmark advance knowledge in hepatitis C virus research
Hepatitis C Virus - Research from the United States and Switzerland in hepatitis C virus provides new insights
Influenza - Reports from the United States and United Kingdom advance knowledge in influenza research
Leukemia - Reports from the United States describe recent advances in leukemia research
Lung Cancer - Findings from Japan and Taiwan describe new data in lung cancer research
Lung Cancer - Findings from the United States advance knowledge in lung cancer research
Lung Cancer - New data from the United States and Austria lluminates research in lung cancer
Lung Cancer - Studies from Italy, France and the United States advance knowledge in lung cancer research
Lymphoma - Recent findings in lymphoma described by researchers from Israel, Taiwan and the United States
Lymphoma - Researchers' findings from the Czech Republic and United States advance lymphoma research
Malaria - Reports from the United States and United Kingdom add new data to malaria research
Medical Devices - Data from the United States and Germany advance knowledge in medical devices research
Osteoporosis - New research from the United States in the area of osteoporosis detailed
Rectal Cancer - New findings from the United States, United Kingdom and Germany in the area of rectal cancer detailed
Rotavirus - Researchers' work from Finland, the United States and Colombia adds to rotavirus body of knowledge
Stroke - Research from Mexico and the United States add new data to stroke body of knowledge
Surgery - Research from the United Kingdom and Hungary in surgery provides new insights
Transplants - Researchers from the United States, Brazil and Germany report details of new studies and findings in the area of transplants
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