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Recurrence prevention in lone paroxysmal atrial fibrillation is better with amiodarone combinations

Published in Clinical Trials Week, October 16th, 2006

AF recurrence prevention in lone paroxysmal AF is more effective with combined perindopril or losartan with amiodarone than amiodarone alone.

According to investigators from People's Republic of China, "The purpose of this trial was to compare the long-term efficacy of low-dose amiodarone with losartan and perindopril (both combined with low-dose amiodarone) for the prevention of atrial fibrillation (AF) recurrence in patients with lone paroxysmal AF."

Y.H. Yin and colleagues at Chongqing University explained, "One-hundred and seventy-seven patients with lone paroxysmal AF were randomly assigned to three treatment groups: group 1 received low-dose...

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