Obesity Therapy

OREXIGEN reports positive 24-week results for Contrave phase III obesity treatment study

Published in Clinical Trials Week, October 16th, 2006

OREXIGEN Therapeutics, Inc., a privately held clinical-stage neuroscience company developing novel strategic approaches to the treatment of obesity, announced that top line results for the company's lead obesity compound, Contrave, demonstrated significant advantages in weight loss in a 24-week multi-center, placebo-controlled phase III trial; the trial will continue unblinded for an additional 24 weeks.

Contrave is a proprietary combination of bupropion, a dopamine and norepinephrine reuptake inhibitor, with one of several different doses of naltrexone, an opioid antagonist used to treat various addictive disorders. The bupropion/naltrexone combination is based on the...

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Source: Clinical Trials Week (2006-10-16)

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