Drug Discovery
Researchers from Max Delbruck Center for Molecular Medicine, Department of Bioinformatics describe findings in drug discovery
Published in Clinical Trials Week, December 18th, 2006
Research findings, "The tumour-Clostridium phenomenon: 50 years of developmental research (Review)," are discussed in a new report. According to a study from Berlin-Buch, Germany, "The tumour-Clostridium phenomenon describes the specific affinity of spore forming anaerobes to tumor growth. The discovery of strictly intratumoral tetanus toxic infections in tumour-bearing mice after intravenous spore administration gave the impulse to search for non-toxic clostridial isolates with tumour-selective properties for clostridial biotherapy, i.e. oncolysis, as well as serologic tumor diagnostics without any toxic side-effects."
"Systematic studies of the oncolytic process and...
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Source: Clinical Trials Week (2006-12-18)
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