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Non-Small Cell Lung Cancer Therapy

Studies in the area of non-small cell lung cancer therapy reported from Roswell Park Cancer Institute

Published in Clinical Trials Week, June 4th, 2007

Data detailed in "Phase I trial of sorafenib in combination with gefitinib in patients with refractory or recurrent non-small cell lung cancer" have been presented. In this recently published article, scientists in the United States conducted a study "To evaluate the combination of sorafenib and gefitinib in patients with advanced non-small cell lung cancer. In this dose-escalation trial, patients received oral sorafenib (200-400 mg) twice daily with gefitinib (250 mg orally) once daily to identify the recommended dose for phase II trials (RDP; part A)."

"The pharmacokinetics of the RDP were characterized further in additional patients (part B) receiving single-agent...

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