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Clinical Trials Week

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Cancer Vaccines



Reports from Memorial Sloan Kettering Cancer Center, Department of Medicine advance knowledge in cancer vaccines



August 27th, 2007

Research findings, "A phase I pilot study of autologous heat shock protein vaccine HSPPC-96 in patients with resected pancreatic adenocarcinoma," are discussed in a new report. "We performed a phase I pilot study to determine if autologous vaccine HSPPC-96 (gp96, Oncophage) could be purified from completely resected pancreas adenocarcinomas, to determine patient tolerance of vaccine and to explore immune responses and clinical outcomes of these patients. Subjects were vaccinated with 5 microg of autologous HSPPC-96 weekly for 4 doses," scientists in the United States report.

"Serial ELISPOT assays of T cells for antitumor reactivity were performed. Subjects received...


Source: Clinical Trials Week (2007-08-27)

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