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Clinical Trials Week

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Systemic Sclerosis Therapy



Research reports from Fred Hutchinson Cancer Research Center provide new insights into systemic sclerosis therapy



August 27th, 2007

Investigators publish new data in the report "High-dose immunosuppressive therapy and autologous hematopoietic cell transplantation for severe systemic sclerosis: long-term follow-up of the US multicenter pilot study." According to recent research from the United States, "More effective therapeutic strategies are required for patients with poor-prognosis systemic sclerosis (SSc). A phase 2 single-arm study of high-dose immunosuppressive therapy (HDIT) and autologous CD34-selected hematopoietic cell transplantation (HCT) was conducted in 34 patients with diffuse cutaneous SSc."

"HDIT included total body irradiation (800 cGy) with lung shielding, cyclophosphamide (120...


Source: Clinical Trials Week (2007-08-27)

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