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Amyotrophic Lateral Sclerosis

Knopp Neurosciences Initiates Phase 1 Clinical Trial of KNS-760704 in ALS Development Program

Published in Clinical Trials Week, October 8th, 2007

Knopp Neurosciences Inc. ("Knopp") announced the initiation of a Phase 1 clinical trial of KNS-760704, a small molecule therapy in development for the treatment of amyotrophic lateral sclerosis (ALS).

This randomized, double-blind, placebo-controlled, single ascending dose study in healthy volunteers is being closely followed by a multiple ascending dose study in healthy subjects. Both studies are designed to evaluate the safety, tolerability and pharmacokinetics of KNS-760704 in human subjects.

"The initiation of Phase 1 represents a significant milestone in Knopp's efforts to develop a safe and effective therapy for a serious unmet medical need,"...

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