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Glioma

TransMolecular Reports Positive Phase 2 Data from Study of (131)Iodine Radiolabeled TM-601 in Recurrent Glioma

Published in Clinical Trials Week, December 3rd, 2007

TransMolecular, Inc., a biotechnology company focused on targeted therapies for cancer, announced the presentation of positive Phase 2 interim results for the intracavitary delivery of its anti-cancer compound (131)I-TM-601 in recurrent malignant glioma at the Society for Neuro-Oncology's 12th Annual Scientific Meeting in Dallas, TX. An interim efficacy analysis from the ongoing, open-label Phase 2 safety and efficacy study demonstrated that the overall survival from the time of recurrence for the highest dosing regimen was estimated at 12.1 months, versus 9.0 months for the lowest dose group. Additionally, no dose-limiting toxicities were observed in the dose-escalation phase of the...

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