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Rigel's R788 Slows Progression of Murine Lupus in Preclinical Studies

Published in Clinical Trials Week, May 12th, 2008

Rigel Pharmaceuticals, Inc. (NASDAQ:RIGL) announced that its lead product candidate, R788, has successfully treated lupus prone mice and significantly improved their survival as reported in a recently published study of the drug candidate. R788 (fostamatinib disodium) is an orally bioavailable syk kinase inhibitor, which has shown clinically significant results in treating patients with rheumatoid arthritis and immune thrombocytopenic purpura in clinical trials. A third clinical trial of R788 in patients with B-cell lymphoma will be completed later this year. Rigel also expects to initiate a Phase 2 clinical trial in lupus in the second half of 2008.

The study, which...

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