Prostate Cancer

Research from M.K. Chadha and co-researchers provides new data on prostate cancer

Published in Clinical Trials Week, October 13th, 2008

According to recent research from the United States, "Preclinical evidence supports the role of estrogen receptor signaling in prostate cancer. In this trial we investigated the tolerability and efficacy of fulvestrant, a pure estrogen receptor antagonist, in the treatment of castration resistant prostate cancer (CRPC)."

"Patients with CRPC were enrolled after written informed consent. Fulvestrant was administered by intramuscular injection at a dose of 500 mg on day 0, then 250 mg on day 14, day 28 and monthly thereafter. History, physical examination, serum prostate specific antigen (PSA) levels and toxicity was evaluated monthly. Radiographic studies were repeated...

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Source: Clinical Trials Week (2008-10-13)

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