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Ovarian Cancer

Reports outline ovarian cancer study findings from Sahlgrenska University

Published in Clinical Trials Week, January 25th, 2010

According to recent research published in the Journal of Nuclear Medicine, "The a-emitter At-211 labeled to a monoclonal antibody has proven safe and effective in treating microscopic ovarian cancer in the abdominal cavity of mice. Women in complete clinical remission after second-line chemotherapy for recurrent ovarian carcinoma were enrolled in a phase I study."

"The aim was to determine the pharmacokinetics for assessing absorbed dose to normal tissues and investigating toxicity. Nine patients underwent laparoscopy 2-5 d before the therapy; a peritoneal catheter was inserted, and the abdominal cavity was inspected to exclude the presence of macroscopic tumor...

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