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Investigators at INSERM have published new data on life sciences in children

Published in Clinical Trials Week, April 26th, 2010

New research, 'Pediatric idiopathic nephrotic syndrome: treatment strategies in steroid dependent and steroid resistant forms,' is the subject of a report. "Idiopathic nephrotic syndrome (INS) is defined as massive proteinuria and hypoalbuminemia associated with dyslipidemia and generalized oedema in most cases. It is thought to be due to a plasma factor of immunologic origin," scientists in France report.

"Most cases are steroid responsive. However, a considerable proportion of children run a steroid dependent course. Calcineurin inhibitors and alkylating agents have been classical treatment strategies for such cases, but specific toxicity limits the use of these...

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