Pharmaceutical Companies
Incyte's Ruxolitinib INCB18424 Meets Primary Endpoint in Second Phase III Study
Published in Clinical Trials Week, March 28th, 2011
2011 MAR 28 -- COMFORT-II, the second pivotal Phase III trial of Incyte Corporation's (Nasdaq: INCY) investigational Janus kinase (JAK) inhibitor, ruxolitinib (INCB18424 or INC424), has met its primary endpoint of significantly reducing spleen size in patients with myelofibrosis (MF), when compared to best available therapy. This trial was conducted by Novartis as part of the Incyte-Novartis worldwide collaboration and license agreement for ruxolitinib, an oral JAK1 and JAK2 inhibitor.
The European study, called COMFORT-II (COntrolled MyeloFibrosis Study with ORal JAK Inhibitor Therapy), showed treatment with ruxolitinib provided a statistically significant...
Want to see the full article?
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Clinical Trials Week
Source: Clinical Trials Week (2011-03-28)
More Articles from Clinical Trials Week
- Clinical Trials Research
Almac - The A to ZED of Automated Walleting for Clinical Trial Supply - Obesity
Amylin and Takeda Voluntarily Suspend Clinical Activities in Obesity Trial - Clinical Trials Research
Cellceutix Reports Production of Its Anti-Cancer Drug Kevetrin Has Begun - Clinical Trials Research
Chronic Myelocytic Leukemia CML Global Clinical Trial Review - Clinical Trials Research
Clinical trial for dry mouth funded by international oral care award - Clinical Trials Research
Colorectal Cancer Global Clinical Trials Review - Q4 2010 - More from this issue of Clinical Trials Week
NewsRx is Social
Follow us on your favorite social network by clicking on a button below:
Top Medical Newsletters
Awards
Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005
Facts & Stats
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.
- Google 2010 PageRank: #2 Among Top Health News and Media Publications
- Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
- Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
- Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry
