Inflammation

Researchers from Harvard University Publish Findings in Inflammation

Published in Clinical Trials Week, October 31st, 2011

2011 OCT 31 -- According to the authors of a study from Boston, Massachusetts, "As a consequence of ischemia-reperfusion injury of whole organ transplants and hypoxia-anoxia of cell transplants, transplantation unavoidably triggers adverse, cytodestructive inflammation within the allograft. Interventions that dampen adverse inflammation may limit the extent and duration of this injury, and preserve tissue function."

"Moreover, these interventions should create a milieu that guides many donor-activated T cells into a tissue-protective phenotype, thus promoting graft acceptance or even tolerance. Hence, it is useful, maybe crucial, to identify the measures...

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Source: Clinical Trials Week (2011-10-31)

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