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Type 2 Diabetes Therapy

Pioglitazone improves glycemic control and lipid profiles in type 2 diabetes

Published in Diabetes Week, June 30th, 2003

by Maria G. Essig, MS, ELS, senior medical writer - Results from a randomized, double-blind, placebo-controlled, clinical trial involving 41 centers in Canada and Spain demonstrated that pioglitazone significantly improved glycemic control and lipid profile in patients with type 2 diabetes.

Matthias Herz and colleagues at Eli Lilly and Company randomly assigned 297 type 2 diabetic patients, 24 to 85 years old, to receive 30 mg pioglitazone daily (n=99), 45 mg pioglitazone daily (n=99), or placebo (n=99) for 16 weeks. Average body mass index (BMI) of the patients was 31.4 kg/m2, and average duration of diabetes was 20.0 months. None of the patients had...

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