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Diabetes Therapy
Insulin therapy regulates somatotropic axis during protracted illness
September 27th, 2004
Intensive insulin therapy can regulate the somatotropic axis during protracted critical illness. "The catabolic state of critical illness has been linked to the suppressed somatotropic GH-IGF-binding protein (IGFBP) axis. In critically ill patients it has been demonstrated that, compared with the conventional approach, which only recommended insulin therapy when blood glucose levels exceeded 12 mmol/L, strict maintenance of blood glucose levels below 6.1 mmol/L with intensive insulin therapy almost halved intensive care mortality, acute renal failure, critical illness polyneuropathy, and bloodstream infections," scientists writing in the Journal of Clinical...
Source: Diabetes Week (2004-09-27)
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