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Bone Healing
Diabetic metabolic state affects healing of large bone defects
September 27th, 2004
Diabetic metabolic state affects healing of large bone defects. According to recent research from Germany, "Insulin-dependent type 1 diabetes mellitus (IDDM) has been shown to after the properties of bone and impair bone repair in both humans and animals. The objective of this study was the detailed histomorphometric evaluation of the influence of the diabetic metabolic state on bone formation and remodeling during bone defect healing depending on the defect size in spontaneously diabetic BB/O(ttawa)K(arlsburg) rats, a rat strain that represents a close homology to IDDM in man. Based on blood-glucose values at the time of surgery, postoperative blood-glucose course, and...
Source: Diabetes Week (2004-09-27)
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