Diabetes Pathogenesis

Gene expression profiles in insulin-sensitive tissues analyzed

Published in Diabetes Week, July 11th, 2005

Scientists have analyzed gene expression profiles in insulin-sensitive tissues from pre-diabetic and diabetic Zucker diabetic fatty rats.

According to recent research from South Korea, "Insulin resistance occurs early in the disease process, preceding the development of type 2 diabetes. Therefore, the identification of molecules that contribute to insulin resistance and leading up to type 2 diabetes is important to elucidate the molecular pathogenesis of the disease. To this end, we characterized gene expression profiles from insulin-sensitive tissues, including adipose tissue, skeletal muscle, and liver tissue of Zucker diabetic fatty (ZDF) rats, a well characterized...

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Source: Diabetes Week (2005-07-11)

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