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Diabetes Week

Susan Hasty, Publisher

Table of Contents . . . April 10th, 2006

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Diabetes Week | Other Publications

Diabetes Complications - Aspirin can inhibit platelet aggregation in most patients with diabetes

Diabetes Epidemiology - EC-SOD gene polymorphism is related to insulin resistance and type 2 diabetes risk

Diabetes Epidemiology - IL-18 promoter polymorphisms are linked to type 1 diabetes predisposition

Diabetes Pathogenesis - Tissue degeneration in hearts could be caused by increased cell-cycle arrest and DNA repair

Type 2 Diabetes - Metformin and TZDs improved fasting hepatic insulin sensitivity and glucose clearance

Angiology - Artery stiffness may be predicted by carotid-femoral pulse wave velocity and carotid stiffness

Business Update - Integrated Security Technologies complete acquisition of oral insulin patent application

Business Update - Korean NIH, Affymetrix to collaborate to identify genes associated with critical diseases

Cardiology - Cardiovascular risk may be mainly associated with waist circumference in Tehranian women

Cardiology - Coronary heart disease deaths in Ireland halved in 15 years

Cardiology - Obesity-related heart disease may be linked to plasma endothelial cell-specific molecule-1

Cardiology - Recent studies add new data to cardiology research

Clinical Trials - KeraCure initiates multicenter pivotal study of wound healing pack in diabetic foot ulcers

Complementary & Alternative Medicine -  Aloe arborescens Miller components show antidiabetic properties in mouse model

Dental Research - Earlier periodontal treatment leads to lower medical costs

Depression - Racial differences in mental health care in diabetics exist among Medicaid patients

Diabetes Care - Quality of diabetes care requires improvement

Diabetes Complications - Diabetic control, disease duration, and onset age predict diabetes complications risk

Diabetes Complications - EDHF-mediated and endothelium-independent relaxations are impaired in diabetic rat arteries

Diabetes Complications - Gangrenous foot development in diabetes mellitus may involve lipoprotein (a) levels

Diabetes Complications - Glucagon-like peptide 1 administration may reduce cardiovascular risk in type 2 diabetes

Diabetes Complications - Glycoxidation of LDL promotes apoptotic pathways and NFkappaB activation in coronary cells

Diabetes Complications - Nai + increase influences ischemia susceptibility in hearts from diabetic mice

Diabetes Complications - Rat neutrophil function and metabolism is altered considerably by diabetes

Diabetes Control - CareSens meter most precise blood glucose meter with bias of less than 5%

Diabetes Control - Endocrinologist-directed intervention aimed at primary care physicians improves diabetes care

Diabetes Control - Glucose homeostasis regulation involves estrogen receptor-alpha

Diabetes Control - Hypoglycemic medication beliefs among type 2 diabetes mediates success rate

Diabetes Control - In primary care setting few patients achieved diabetes control targets

Diabetes Control - Insulin glargine plus insulin lispro improved glycemic control in type 1 diabetes

Diabetes Control - Insulin glargine plus oral hypoglycemic agents provide glycemic control in type 2 diabetes

Diabetes Diagnosis - Genetic tests can be crucial for correct classification of diabetes type

Diabetes Diagnosis - Primary care practices may improve undiagnosed diabetes detection and improve 1-year outcomes

Diabetes Diagnosis - Retinopathy signs plus a family history of diabetes predict subsequent diabetes risk

Diabetes Education - Diabetes education for youth involving puppets allowed them feel in control of the situation

Diabetes Epidemiology - Benefits of diet in Murcia, Spain do not counteract obesity-related risk factors

Diabetes Epidemiology - Interleukin-12p40 gene polymorphism did not seem to play role in type 1 diabetes mellitus

Diabetes Epidemiology - Reports describe recent advances in diabetes epidemiology research

Diabetes Epidemiology - Urinary albumin excretion and renal disease related to diabetes are linked to genetics

Diabetes Management - Healthways announces new agreement with Middle Tennessee Medical Center for diabetes care

Diabetes Pathogenesis - Baroreflex gain are progressively reduced with increasing severity of insulin resistance

Diabetes Pathogenesis - Beta-cell GSIS dysfunction may show fetal survival adaptations that predispose to diabetes

Diabetes Pathogenesis - COX2 (PTGS2) inhibitors augment hexose transport rate in insulin- and AMPK alpha-independent way

Diabetes Pathogenesis - Ca2+ overload and high Ca2+ transport are linked to salivary cell impairment in diabetes

Diabetes Pathogenesis - Decrease in PI-3K/AKT1 survival signaling mediates DN-HNF-1alpha-induced apoptosis

Diabetes Pathogenesis - Diabetes only affects nNOS-containing myenteric neurons without heme oxygenase 2

Diabetes Pathogenesis - Findings describe new data in diabetes pathogenesis research

Diabetes Pathogenesis - Glucagon works to induce ERK 1/2 phosphorylation and raise mesangial cell proliferation

Diabetes Pathogenesis - HNF-4 alpha is essential for glucose stimulated insulin secretion by pancreatic beta-cells

Diabetes Pathogenesis - MCH-/- mice are resistant to aging-associated raises in body weight and insulin resistance

Diabetes Pathogenesis - New findings in the area of diabetes pathogenesis described

Diabetes Pathogenesis - New findings in the area of diabetes pathogenesis detailed

Diabetes Pathogenesis - Phosphorylation of JNK in diabetic rat sensory neurons may impair nerve conduction

Diabetes Pathogenesis - RAS and NOS3 polymorphisms do not seem to influence cardiovascular disease in diabetics

Diabetes Pathogenesis - Rapid infancy weight gain in preterms was slightly related to higher insulin levels

Diabetes Pathogenesis - Recent findings in diabetes pathogenesis provide new insights

Diabetes Pathogenesis - Research in diabetes pathogenesis provides new insights

Diabetes Pathogenesis - Researchers detail new studies and findings in the area of diabetes pathogenesis

Diabetes Pathogenesis - Smad7 expression in beta cells disrupts TGF-beta signaling and induces reversible diabetes

Diabetes Pathogenesis - Urinary oxidative stress markers may indicate vascular complication risk in type 1 diabetes

Diabetes Therapy -  Salacia oblonga root improves postprandial hyperlipidemia and hepatic steatosis in diabetes

Diabetes Therapy - Behavioral assessment and intervention in pediatric diabetes is reviewed

Diabetes Therapy - Diabetes mellitus prevalence has increased steadily in Germany to reach 6.45%

Diabetes Therapy - Diabetic nephropathy progression is delayed by probucol

Diabetes Therapy - Duloxetine offers diabetic neuropathy treatment

Diabetes Therapy - Emotional problems in diabetes patients need increased recognition

Diabetes Therapy - Exenatide dose reduced postprandial plasma glucose excursions in type 2 diabetes

Diabetes Therapy - Glycemic control can be achieved with both glargine plus metformin and NPH plus metformin

Diabetes Therapy - Insulin administration route did not alter glucose metabolism

Diabetes Therapy - Insulin aspart was well tolerated and effective during long-term type 1 diabetes treatment

Diabetes Therapy - Insulin release in novel drug delivery system depends on polymer swelling and crosslinking

Diabetes Therapy - Lisinopril plus telmisartan may prevent diabetic nephropathy type 2 diabetes, hypertension

Diabetes Therapy - NCX4016 has protective effect against ischemia-reperfusion injury in diabetic rat hearts

Diabetes Therapy - Okchun-San-C may lower blood glucose level in type 2 diabetic patients

Diabetes Therapy - Pioglitazone raises adiponectin levels and reduces TNF-alpha levels in type 2 diabetics

Diabetes Therapy - Pioglitazone's insulin-sensitizing offers advantage over gliclazide for glycemic control

Diabetes Therapy - Postprandial lipemia in diabetics is restored to normal by insulin sensitization with pioglitazone

Diabetes Therapy - Reports describe recent advances in diabetes therapy research

Diabetes Therapy - Researchers' findings advance diabetes therapy research

Diabetes Therapy - Restenosis in diabetics with coronary lesions was reduced by radiation after stent implant

Diabetes Therapy - Urotensin-II receptor antagonist palosuran improves pancreatic and renal function in diabetic rats

Diagnostics - Abbott receives U.S. FDA 510K clearance to market blood glucose monitoring system

Diet & Nutrition - Studies add new findings to diet & nutrition body of knowledge

Drug Delivery - Scientists use wireless MicroChips to control drug release over time

Drug Development - Glibenclamide in single oral dose does not reduce pain-free or maximal walking distance

Drug Discovery - CytRx provides 2006 update on RNAi-based drug-discovery programs

Endocrinology - Gap junction coupled KATP channel activity plays key role in regulating insulin secretion

Endocrinology - Rapid Ca2+ uptake by SERCA pump controls insulin secretion amount

Finance - Keryx reports 2005 increase in cash, other assets spurred by common stock offering

Finance - Point Therapeutics reports a net loss of $5,899,000 for fourth quarter

Genetics & Genomics - GSTT1 gene may contribute to type 2 diabetes mellitus development

Healthcare Coverage - Diabetes advocates urge Senate HELP Committee to reject Enzi health insurance legislation

Healthcare Coverage - Healthways expands HealthPlus of Michigan contract to provide disease-management services

Healthcare Coverage - Mutual of Omaha to offer Healthways' myhealthIQ wellness program to group health customers

Hyperglycemia - 5-HT reduces hyperphagia in NPY-overexpressing rat through action on 5-HT2A receptors

Hypertension - Hypertension and cardiovascular disease risk are linked to age, diabetes, and albuminuria

Hypertension - Hypertension may be adversely affected by swimming therapy in older women

Hypertension - In prehypertensives, impaired glucose tolerance raised cardiovascular disease risk

Hypertension - New data illuminates research in hypertension

Information Technology - Invivodata integrates devices for patient-reported data recording in clinical trial

Kidney Transplantation - Findings advance knowledge in kidney transplantation research

Mergers & Acquisitions - Fisher Scientific expands presence in molecular diagnostics, will acquire Athena Diagnostics

Neuropathic Pain - Lacosamide results statistically significant in diabetic neuropathic pain phase III trial

Non-Alcoholic Steatohepatitis - Non-alcoholic steatohepatitis predictors of fibrosis identified

Obesity Complications - Carotid artery stiffness and C-reactive protein were linked to metabolic syndrome in obese

Obesity Complications - Macrophage-secreted factors influence inflammatory and insulin responses in adipocytes

Obesity Pathogenesis - Findings in obesity pathogenesis provide new insights

Obesity Pathogenesis - p38MAPK negatively influences adipogenesis by inhibiting C/EBP beta and PPAR gamma transcription

Obstetrics - Birth weight may be associated with maternal glucose levels during third trimester

Obstetrics - Changes in fetal echocardiography referral trends are focus of review

Obstetrics - Rise in maternal pregestational diabetes corresponds to increased birth complications

Patents - Patent issued to the University of Pittsburgh for 2-methoxyestradiol for diabetes

Pediatric Diabetes - Adolescents with diabetes have friendships that are similar to those among healthy

Personnel - Sirna Therapeutics announces members of scientific advisory board

Physiology - RNA interference-based screen identifies MAP4K4/NIK as a negative regulator

Surgical Technology - Stent registry safety data favors Taxus over Cypher in complex diabetic patients

Transplant Medicine - Novel method may allow transplant of islet cells from single donor into multiple recipients

Type 1 Diabetes - Self-management-based patient education program for hypoglycemia therapy in diabetes is adequate

Type 1 Diabetes - Serum CXCL10 level may be used to assess pathophysiology of type 1 diabetes disease course

Type 2 Diabetes - CytRx's RNAi screening technology supported by publication of scientific article, says company

Type 2 Diabetes - Dopamine D3-RA had a positive effect on renal morphology and albuminuria in type 2 diabetes

Type 2 Diabetes - Gly482Ser variant in PPARGC1 plays a role in type 2 diabetes risk

Type 2 Diabetes - Hypertriglyceridemia, waist-hip ratio, and family T2DM history increase diabetes risk

Type 2 Diabetes - Neuroanatomical framework for the role of the brain in type 2 diabetes was determined

Type 2 Diabetes - Postprandial deterioration of endothelial dysfunction in diabetes is decreased by vitamin C

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