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Diabetes Complications
EDHF-mediated and endothelium-independent relaxations are impaired in diabetic rat arteries
April 10th, 2006
EDHF-mediated hyperpolarization and relaxation and endothelium-independent relaxations are both impaired in arteries of type 2 diabetic rats. According to recent research published in the Journal of Hypertension, "Diabetes mellitus is an important risk factor for cardiovascular diseases, and vasodilator dysfunction may contribute to vascular complications in diabetes. We previously demonstrated that the angiotensin II receptor blocker (ARB) corrected the impaired endothelium-derived hyperpolarizing factor (EDHF)-mediated arterial hyperpolarization and relaxation associated with hypertension or aging, partially independently of blood pressure." ...
Source: Diabetes Week (2006-04-10)
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