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Diabetes Complications
Rat neutrophil function and metabolism is altered considerably by diabetes
April 10th, 2006
Diabetes causes marked changes in function and metabolism of rat neutrophils. "Several studies have shown impairment of neutrophil function, a disorder that contributes to the high incidence of infections in diabetes. Since glucose and glutamine play a key role in neutrophil function, we investigated their metabolism in neutrophils obtained from the peritoneal cavity of streptozotocin-induced diabetic rats," scientists in Brazil report. T.C. Alba-Loureiro and colleagues working with the University Sao Paulo described, "The activities of hexokinase, glucose-6-phosphate dehydrogenase (G6PDH), phosphofructokinase (PFK), citrate synthase,...
Source: Diabetes Week (2006-04-10)
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