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Diabetes Epidemiology
EC-SOD gene polymorphism is related to insulin resistance and type 2 diabetes risk
April 10th, 2006
Extracellular superoxide dismutase gene polymorphism is associated with insulin resistance and the susceptibility to type 2 diabetes. "Oxidative stress has been implicated in pancreatic beta-cell damage, insulin resistance and vascular function in diabetic patients and the dysfunction of antioxidant enzymes may be associated with the pathogenesis of diabetes. Extracellular superoxide dismutase (EC-SOD) is found in the extracellular matrix of tissues and the major scavenger of superoxide radical," investigators in Japan report. M. Tamai and colleagues at Wakayama Medical University proposed "To investigate the role of genetic variability for the...
Source: Diabetes Week (2006-04-10)
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