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Diabetes Pathogenesis

RAS and NOS3 polymorphisms do not seem to influence cardiovascular disease in diabetics

"Cardiovascular disease (CVD) is a major complication of type 2 diabetes mellitus. The renin-angiotensin system (RAS) and nitric oxide production are both important regulators of vascular function and blood pressure. Genes encoding proteins involved in these pathways are candidates for a contribution to CVD in diabetic patients," investigators in the United States report.

K.P. Burdon and colleagues at Wake Forest University examined "variants of the angiotensinogen (AGT), angiotensin converting enzyme (ACE),...

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