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Diabetes Week

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Diabetes Pathogenesis



Recent findings in diabetes pathogenesis provide new insights



April 10th, 2006

Diabetes pathogenesis research advances have been reported from the United States, Finland and Austria.

Study 1: Diabetic adolescents have significant insulin resistance, but retain a first-phase insulin response to glucose.

"Type 2 diabetes mellitus (T2DM) is estimated to account for 10-45% of incident pediatric diabetes cases. Our objective was to characterize the metabolic defects underlying T2DM in adolescents and young adults. We conducted a cross-sectional study of islet function and insulin sensitivity in 16 adolescents with T2DM and 13 obese (OB) and 13 lean (LN) age-matched nondiabetic subjects at a University Medical Center," scientists...


Source: Diabetes Week (2006-04-10)

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