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Diabetes Week

Susan Hasty, Publisher

Table of Contents . . . April 24th, 2006

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Diabetes Week | Other Publications

Diabetes Epidemiology - Amino acid variants in activating transcription factor 6 gene linked to type 2 diabetes

Diabetes Pathogenesis - Chaperonin 60 may indicate mitochondrial dysfunction in diabetic central nervous system

Diabetes Pathogenesis - Increased pp38MAPK and pHSP25 comprise acute adaptation to glycemic stress in diabetes

Diabetes Therapy - Glucose-dependent insulinotropic peptides are long-acting stable analogues for diabetes therapy

Diabetic Nephropathy - Diabetic nephropathy diagnosis allows identification of patients with high cardiorenal risk

Alzheimer Disease - Increased cortical atrophy in type 2 diabetes mellitus may increase Alzheimer disease risk

Angiology - Clopidogrel withdrawal is linked to proinflammatory and prothrombotic effects in diabetes

Breast Cancer - Breast cancer risk does not appear affected by higher serum hemoglobin A1c levels

Business Update - Elixir Pharmaceuticals acquires late-stage product for the treatment of type II diabetes

Cardiovascular Disease - Low ankle-brachial pressure index predicts high CVD risk independent of metabolic syndrome

Clinical Trials - Exelixis initiates Phase II clinical program for XL784 in diabetic nephropathy

Collaborations - Santen, Oakwood Laboratories sign deal for development of diabetic macular edema technology

Complementary & Alternative Medicine - Aged garlic extract retards progression of coronary artery calcification

Diabetes Complications - Albuminuria lowering in hypertension and diabetes patients appears to be beneficial

Diabetes Complications - Amadori products may play a role in the development of diabetic heart disease

Diabetes Complications - Angiotensin-converting enzyme-inhibitors may raise long-term end-stage renal failure risk

Diabetes Complications - Coronary risk prediction for those with and without diabetes is the same

Diabetes Complications - Depression therapy satisfaction differed between diabetics of different ethnic groups

Diabetes Complications - Diabetic retinopathy can be detected by serum anti-aldolase autoantibody

Diabetes Complications - Diabetic retinopathy changes glial cell swelling characteristics

Diabetes Complications - Distal sensory polyneuropathy in diabetes mellitus is common and has many sources

Diabetes Complications - Ethnicity variations in LVM, EDV, and stroke volume are related to abnormal glucose metabolism

Diabetes Complications - New findings in the area of diabetes complications described

Diabetes Complications - Norepinephrine overflow is impaired in failing hearts from Zucker diabetic fatty rats

Diabetes Complications - Reduced membrane permeability to Ca2+ depressed cardiac function in diabetic mice

Diabetes Control - DexCom receives FDA approval for STS Continuous Glucose Monitoring System

Diabetes Control - New long-acting insulin analog Levemir now available in United States

Diabetes Control - Poor blood sugar control linked to depression in youth with diabetes

Diabetes Diagnosis - Dobutamine stress echocardiography can assess diabetes-related cardiovascular morbidity

Diabetes Epidemiology - ADIPOR2 variants have a minor contribution to diabetes risk

Diabetes Epidemiology - AMPK genes PRK4A2, PRKAB1, and PRK4B1 plus BMI appear to be linked to type 2 diabetes

Diabetes Epidemiology - New findings in the area of diabetes epidemiology detailed

Diabetes Management - Diabetes education results in significant improvement in diabetes management

Diabetes Monitoring - FDA approval of continuous glucose sensor accelerates development of artificial pancreas

Diabetes Monitoring - FDA issues clearance for AgaMatrix's high-accuracy blood glucose monitor

Diabetes Pathogenesis - Acute-phase reactants are related to arterial stiffness in type 2 diabetes mellitus

Diabetes Pathogenesis - AdipoR1 and AdipoR2 do not appear to have a key role in insulin sensitivity modulation

Diabetes Pathogenesis - Basal FFA production may be induced by decline in FFA re-esterification in diabetic rat

Diabetes Pathogenesis - Diminished PKC isoenzymes levels influence lead to disturbed insulin secretion in GK rat

Diabetes Pathogenesis - Findings advance knowledge in diabetes pathogenesis research

Diabetes Pathogenesis - Increased monocytic activity and inflammation markers are found in type 1 diabetes

Diabetes Pathogenesis - MCHr1 deficiency raises insulin sensitivity in obese leptin-deficient, but not body weight

Diabetes Pathogenesis - Metabolic syndrome traits in families may be linked to pleiotropic gene effects or environment

Diabetes Pathogenesis - Minimal breast-feeding and early cow milk/late gluten introduction raises diabetes risk

Diabetes Pathogenesis - New data illuminates research in diabetes pathogenesis

Diabetes Pathogenesis - New findings in diabetes pathogenesis described

Diabetes Pathogenesis - Protein tyrosine phosphatase-N1 variants are linked to coronary calcified plaque in diabetes

Diabetes Pathogenesis - Psychological distress is not related to diabetes incidence in American Indians

Diabetes Pathogenesis - Relationship between reduced antioxidant status and insulin resistance state observed in nonobese children

Diabetes Pathogenesis - Reports add new data to diabetes pathogenesis research

Diabetes Pathogenesis - Reports advance knowledge in diabetes pathogenesis research

Diabetes Pathogenesis - Researchers' work adds to diabetes pathogenesis body of knowledge

Diabetes Pathogenesis - Respiratory muscles endurance is impaired by a decline in MMV values

Diabetes Pathogenesis - Suppressor of cytokine signaling 3 overexpression in adipose tissue causes insulin resistance

Diabetes Pathogenesis - Visceral adipose tissue measurement site influences metabolic syndrome diagnosis definitions

Diabetes Pathogenesis - alpha1 -Adrenoceptors cause glucose uptake by mediating AMPK activation in muscle cells

Diabetes Prevention - Hormone therapy may have antidiabetic effect but may also increase risk of heart disease

Diabetes Research - Odd-looking pig is the focus of research into diabetes, infertility, and heart disease

Diabetes Risk Factors - Increased diabetes risk is seen in women with gestational diabetes using injectable progestin

Diabetes Therapy - Addition of rapid-acting insulin to basal insulin therapy in diabetes may offer better control

Diabetes Therapy - Antecedent hypoglycemia does not alter epinephrine-induced lipolysis in type 1 diabetes

Diabetes Therapy - Asparagus adscendens stimulates insulin secretion, insulin action and inhibits starch digestion

Diabetes Therapy - Benfluorex in combination with sulfonylurea was beneficial for type 2 diabetics

Diabetes Therapy - Caffeic acid phenethyl ester improves IGFs secretion and gene expression changes in diabetic rats

Diabetes Therapy - Findings advance knowledge in diabetes therapy research

Diabetes Therapy - Hospitals fail to record concurrent diabetes diagnoses during hospitalization

Diabetes Therapy - Incretin mimetics and dipeptidyl peptidase-IV inhibitors offer new type 2 diabetes therapies

Diabetes Therapy - Recent findings in diabetes therapy provide new insights

Diabetes Therapy - Research add new data to diabetes therapy body of knowledge

Diabetes Therapy - Researchers detail new studies and findings in the area of diabetes therapy

Diabetes Therapy - Researchers' data advance diabetes therapy research

Diabetes Therapy - Researchers' findings advance diabetes therapy research

Diabetes Therapy - Researchers' work adds to diabetes therapy body of knowledge

Diabetes Therapy - Takeda submits new drug application for extended-release type 2 diabetes medication, ACTOplus met

Diabetic Nephropathy - Prepubertal diabetes onset seems to prolong development time of end-stage renal disease

Diabetic Neuropathy - First consensus guidelines presented for diabetes-related pain

Diabetic Neuropathy - Nerve growth factor delays nociceptive deficits in diabetic neuropathy model

Diagnostics - Cockcroft-Gault formula used to improve glomerular filtration rate prediction in diabetics

Diet & Nutrition - Casitas b-lineage lymphoma-deficient mice protected against obesity and diabetes

Diet & Nutrition - Intestine and kidney contribute to glucose fluxes when nutritional conditions are changing

Diet & Nutrition - Mixed meal does not alter splanchnic cortisol production or D4 to D3 cortisol conversion

Diet & Nutrition - New scientific review shows vegetarian diets more effective for weight loss

Endocrinology - Endocrine stem or progenitor cells may be within adult pancreas epithelial compartment

Endocrinology - Insulin regulates neuronal glucose uptake by promoting glucose transporter GLUT3 translocation

Endocrinology - Low-potency PARP inhibitors raise insulin synthesis by increasing MafA gene transcription

Endocrinology - Proopiomelanocortin neurons in hypothalamus may mediate leptin signaling via POMC-derived peptides

Genetics & Genomics - Researchers describe findings in genetics & genomics studies

Geriatrics - Survey shows public doesn't realize how vulnerable older Americans are to chronic diseases

Gestational Diabetes - Diabetes programs during pregnancy may not translate to better long-term management

Gestational Diabetes - Gestational diabetes and autoantibodies may predict women at risk for long-term diabetes

Gestational Diabetes - Predictors of postpartum diabetes in women with gestational diabetes are identified.

Healthcare Costs - American Diabetes Association urges Congress to increase diabetes prevention funding

Natural Products - Oyster extract induces triglyceride-lowering activity and antihypertensive effect rat model

Natural Products - Two cannabinoid receptor antagonists developed for obesity and metabolic syndrome therapy

Obesity Complications - Obese-diabetic coronary artery bypass graft patients have high postoperative morbidity

Obesity Pathogenesis - New findings in the area of obesity pathogenesis described

Obesity Preventive Medicine - Multilevel physical activity intervention program lowered sedentary behavior after 6 months

Obstetrics - In women with polycystic ovary syndrome, Glucophage may enhance success of live births

Patents - DexCom announces U.S. Patent and Trademark Office to re-examine Abbott patents at issue

Proteomics - Syntaxin-3, OSBP-related protein 3, PPAR-gamma and glycophorin linked to adipogenesis

Stem Cell Research - Juvenile Diabetes Research Foundation joins Kansas coalition to protect stem cell access

Type 1 Diabetes - 1,25-dihydroxyvitamin D3 protects pancreatic islets and may prevent type 1 diabetes

Type 1 Diabetes - Diabetes trial to launch at Children's Hospital of Pittsburgh

Type 2 Diabetes - Amylin initiates once-weekly Exenatide LAR clinical study in type 2 diabetes

Type 2 Diabetes - New drug application for Galvus as diabetes treatment accepted for review by U.S. FDA

Women's Health - Book provides comprehensive guide to women's health problems and treatments

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