Diabetes Week

Diabetes Complications - Diabetes raises adverse neurocognitive outcome after coronary artery bypass grafting surgery

Diabetes Control - Caloric restriction ameliorates oxidative and inflammatory effects of diabetes in the brain

Diabetes Prevention - Peroxisome proliferator-activated receptor-alpha agonism prevents type 2 diabetes

Diabetic Nephropathy - Angiotensin II-dependent Src and Smad1 signaling pathway is key to diabetic nephropathy

Insulin Resistance - Insulin resistance accelerates muscle wasting by activation of ubiquitin-proteasome pathway

Alzheimer Disease - In Alzheimer disease, beta-amyloid toxicity may be mediated by oxidation of GRX-1 and TRX-1

Alzheimer Disease - Kurve Technology reports clinical success in Alzheimer disease study

Angina - Variant angina and significant coronary stenosis often resemble acute coronary syndrome

Autoimmune Diseases - PTPN22 plays an important role in type 1 diabetes and other autoimmune diseases

Business Update - Mediatech announces new pancreas preservation solution for islet cell transplantation

Cardiomyocytes - Circadian clock within cardiomyocyte is essential for heart responsiveness to fatty acids

Cardiovascular Disease - Myocardial perfusion scintigraphy may be diagnostic tool for asymptomatic patients with diabetes

Cardiovascular Disease - Screening asymptomatic diabetics for coronary artery disease may not be cost effective

Cataracts - Repeated intravitreal triamcinolone injections lose efficacy in diabetic macular edema

Collaborations - Arena Pharmaceuticals reports Ortho-McNeil extends research term

Diabetes & Angiology - Cutting balloon angioplasty is effective for diabetic patients with in-stent restenosis

Diabetes & Obesity - Insulin-resistance is closely associated with metabolic syndrome components in obese

Diabetes & Obesity - Pro12Ala variant of PPAR-gamma2 gene is linked to high diastolic blood pressure in obese diabetics

Diabetes Complications - Diabetes is linked to higher passive ankle stiffness and lower dorsiflexion range of motion

Diabetes Complications - Diabetes mellitus reduces the antiarrhythmic effect of ion channel blockers

Diabetes Complications - Diabetes prevalence predict demand for hospital services overall

Diabetes Complications - Diabetic patients benefit less than nondiabetic patients from infrageniculate bypass surgery

Diabetes Complications - Home and office blood pressure were not adequately controlled in most diabetic hypertensives

Diabetes Complications - Novel method was developed to quantify in vivo transferrin glycation in diabetes mellitus

Diabetes Complications - Patients with diabetic macular edema may be better managed with optical coherence tomography

Diabetes Complications - Patients with proliferative diabetic retinopathy may form nephropathy

Diabetes Complications - Plasma total homocysteine is a risk indicator for cardiovascular disease in diabetic children

Diabetes Complications - PPAR alpha deficiency raises risk of maternal abortion and neonatal mortality in murine pregnancy

Diabetes Complications - Prorenin receptor contributes to regulation of renal cortical COX-2 expression

Diabetes Complications - Type 2 diabetes-related mortality at older ages is lower than expected

Diabetes Control - Diabetes care transfer from parent to youths requires proper education and attention

Diabetes Control - Diabetes healthcare services were reduced by VA Care Coordination Home Telehealth program

Diabetes Control - Diabetes is perceived as stressful for adolescents and mothers

Diabetes Control - In a diabetic rat model, garlic oil can improve oral glucose tolerance

Diabetes Epidemiology - Pro12Ala variant of PPARG2 gene plus high intake of oleic acid is linked to type 2 diabetes

Diabetes Epidemiology - Type 2 diabetes and metabolic syndrome therapy in adolescents is often suboptimal

Diabetes Gastroparesis - In diabetic gastroparesis, vagal function and regulation of ghrelin levels are impaired

Diabetes Management - National survey shows women overlook warning signs of poor blood sugar management

Diabetes Pathogenesis - Cytoplasmic buildup of long-chain coenzyme A esters activates K_ATP and inhibits Kir2.1 channels

Diabetes Pathogenesis - Exercise and dexamethasone oppositely modulate beta-cell function in rat model

Diabetes Pathogenesis - Nitric oxide mediates downregulation of leptin production by 3T3-L1 adipocytes

Diabetes Pathogenesis - Perturbation of glucose flux in the liver causes hepatic insulin resistance and hyperglycemia

Diabetes Prevention - Release of acetylcholine by Hon-Chi raises insulin secretion and may prevent type 2 diabetes

Diabetes Research - Pine tree bark reduces diabetic microangiopathy

Diabetes Therapy - Metabolic control improves after depletion of liver x receptors in mouse model

Diabetes Therapy - Multiple oral antidiabetic agents may indicate more severe, uncontrolled diabetes

Diabetes Therapy - Pancreatic islet transplants revascularize when cocultured with angiogenesis stimulators beforehand

Diabetic Dermopathy - Diabetic dermopathy is key clinical sign for more severe neuropathic impairment

Diabetic Macular Edema - MacuSight initiates first phase 1 study of sirolimus formulation for diabetic macular edema

Diabetic Myocardium - Insulin deficiency mediates expression of Hsc70 in diabetic myocardium

Diabetic Retinopathy - Diabetic retinopathy pathology is altered by pigment epithelium-derived factor

Diet & Nutrition - High glucose and CML-BSA modulate matrix metalloproteinase release in human endothelial cells

Diet & Nutrition - Nutrients mediate phosphorylation and translocation of Foxo1 in C57BL/6 and db/db mice

Endocrinology - Insulin-like actions displayed by a naphthoquinone derivative

Endocrinology - Low plasma adiponectin levels is an independent predictors of glucose intolerance

Endocrinology - Metabolic factors can directly modulate primate somatotrope function in primate model

Endocrinology - Metformin reduces lipolysis in primary rat adipocytes stimulated by TNF-alpha or isoproterenol

Endocrinology - Proinsulin C-peptide elicits disaggregation of insulin

Finance - CytRx awarded federal grant to explore novel type 2 diabetes and obesity treatment

Fitness & Wellness - Resistance exercise has a dehydroepiandrosterone sulfate-lowering effect

Genetics & Genomics - Consortium develops map of vital area in major histocompatibility complex of human genome

Hearing Loss - SLC19A2 deletion causes selective inner hair cell loss and auditory neuropathy phenotype

Hyperglycemia - Antihyperglycemic activity is observed in the selective PPAR gamma modulator KR-62980

Hyperglycemia - In hyperglycemic mice, cell specificity to tolbutamide is impaired in beta-cells

Hyperglycemia - Strict glycemic control improves patient mortality and in-hospital morbidity

Hypertension - High urinary calcium excretion in hypertension and kidney stone disease has genetic basis

Insulin Binding - Insulin binding and the active insulin receptor conformation are investigated

Insulin Release - Oleanolic acid increases acetylcholine release, which raises insulin secretion in rats

Insulin Resistance - Nutritional determinants of insulin resistance can be used to modify diets for prevention

Insulin Therapy - Glycemic control in acute cardiac care settings reduces cost, morbidity, and mortality

Market Analysis - Type 2 diabetes drugs from Merck and Novartis predicted to become blockbusters by 2015

Mergers & Acquisitions - Matria Healthcare agrees to sell diabetes services business Dia Real in $33 million deal

Metabolic Disorders - Kalypsys nearing completion of phase Ia study of KD3010 for metabolic disorders