Diabetes Complications
Diabetes mellitus reduces the antiarrhythmic effect of ion channel blockers
Published in Diabetes Week, October 23rd, 2006
According to recent research from Japan, "We designed the present study to examine whether diabetes mellitus affects the antiarrhythmic effect of flecainide, a sodium channel blocker, E-4031, a potassium channel blocker, and verapamil, a calcium channel blocker, in diabetic rats. The experiments were performed in intact and diabetic rats 2, 4, and 6 wk after administration of streptozotocin."
I. Ito and colleagues at Osaka University explained, "Rats were anesthetized with halothane and monitored continuously for arterial blood pressure and premature ventricular...
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Source: Diabetes Week (2006-10-23)
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