Type 1 Diabetes Immunology
Scientists at J.N. Medical College, Department of Biochemistry publish new data on type 1 diabetes immunology
Published in Diabetes Week, January 1st, 2007
Research findings, "Reactive oxygen species damaged human serum albumin in patients with type 1 diabetes mellitus: biochemical and immunological studies," are discussed in a new report. "The role of hydroxyl radical (.OH) damaged human serum albumin (HSA) in type 1 diabetes has been investigated in the present study. Hydroxyl radical induced modification on HSA has been studied by UV absorption spectroscopy, ANS fluorescence and carbonyl estimation," scientists in India report.
"Hydroxyl radical modified HSA was found to be highly immunogenic in rabbits as compared to native HSA. The binding characteristics of circulating autoantibodies in type 1 diabetes patients...
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Source: Diabetes Week (2007-01-01)
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