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AstraZeneca, Bristol-Myers Squibb announce alliance to develop diabetes compounds

Published in Diabetes Week, February 12th, 2007

AstraZeneca and Bristol-Myers Squibb Company (BMY) announced a collaboration to develop and commercialize two investigational compounds being studied for the treatment of Type 2 diabetes.

Both compounds were discovered by Bristol-Myers Squibb.

Saxagliptin, a dipeptidyl peptidase-4 (DPP-4) inhibitor, is currently in phase III development. Upon successful completion of the development program, the companies plan to file for U.S. regulatory approval of saxagliptin during the first half of 2008. Dapagliflozin (previously referred to as BMS-512148), a sodium-glucose cotransporter-2 (SGLT2) inhibitor, is currently in phase IIb development. The...

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