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Obesity and Diabetes

Research in the area of obesity and diabetes reported from University of Essex, Department of Biological Sciences

Published in Diabetes Week, May 7th, 2007

Scientists discuss in "Advanced glycation endproducts: what is their relevance to diabetic complications" new findings in obesity and diabetes. "Glycation is a major cause of spontaneous damage to proteins in physiological systems. This is exacerbated in diabetes as a consequence of the increase in glucose and other saccharides derivatives in plasma and at the sites of vascular complications," scientists in the United Kingdom report.

"Protein damage by the formation of early glycation adducts is limited to lysine side chain and N-terminal amino groups whereas later stage adducts, advanced glycation endproducts (AGEs), modify these and also arginine and cysteine...

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