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Northwestern University

Compound is key coordinator of clock and metabolism

Published in Diabetes Week, April 6th, 2009

Our circadian clock, or biological timing system, governs our daily cycles of feeding, activity and sleep. Research using cells has produced a solid portrait of the clock at the genetic and molecular levels, but understanding how those mechanisms contribute to the health and disease of living animals, including humans, has been elusive.

Now researchers at Northwestern University and Washington University School of Medicine, in a new study to be published online March 19 by the journal Science, have uncovered a surprising new connection between the circadian clock and metabolism in mammals.

The findings could help researchers better understand the...

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