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Diabetes
Researchers at Johns Hopkins University, Medical Department have published new data on diabetes
June 15th, 2009
According to a study from the United States, "Anti-mouse thymocyte globulin (mATG) prevents, as well as reverses, type 1 diabetes in NOD mice, through mechanisms involving modulation of the immunoregulatory activities of T lymphocytes. Dendritic cells (DC) play a pivotal role in the generation of T cell responses, including those relevant to the autoreactive T cells enabling type I diabetes." "As Abs against DC are likely generated during production of mATG, we examined the impact of this preparation on the phenotype and function of DC to elucidate novel mechanisms underlying its beneficial activities. In vivo, mATG treatment transiently induced the trafficking of...
Source: Diabetes Week (2009-06-15)
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