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Diabetes
Studies from E. Zherebitskaya and co-researchers in the area of diabetes published
July 13th, 2009
According to recent research published in the journal Diabetes, "Reactive oxygen species (ROS) are pro-oxidant factors in distal neurodegeneration in diabetes. We tested the hypothesis that sensory neurons exposed to type 1 diabetes would exhibit. enhanced ROS and oxidative stress and determined whether this stress was associated with abnormal axon outgrowth." "Lumbar dorsal root ganglia sensory neurons from normal or 3- to 5-month streptozotocin (STZ)-diabetic rats were cultured with 10 or 25-50 mmol/l glucose. Cell survival and axon outgrowth were assessed. ROS were analyzed using confocal microscopy. Immunofluorescent staining detected expression of manganese...
Source: Diabetes Week (2009-07-13)
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