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Angiotensins
New angiotensins study findings recently were reported by researchers at Jilin University
July 13th, 2009
According to recent research published in the journal Nephrology Dialysis Transplantation, "Angiotensin II type 1 receptor (AT1) plays an important role in the development of diabetic nephropathy (DN). However, the roles played by 12-lipoxygenase (12-LO) in the AT1 expression in glomerular cells exposed to high glucose (HG) and diabetic glomeruli remain unclear." "Our objective in the present study was to investigate the role of 12-LO in the AT1 expression in glomerular cells and glomeruli under diabetic conditions. Mesangial cells (MCs), podocytes and glomeruli isolated from rats were used in this study. The rats fed a high fat diet received low-dose...
Source: Diabetes Week (2009-07-13)
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