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Disease Risk Factor Week

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Aarhus University Hospital



Anterior lumbar interbody fusion platelet-rich plasma did not help fusion rate



October 17th, 2004

At the concentration used in this study, platelet-rich plasma (PRP) did not improve the bone-forming capacity of beta tricalcium phosphate (beta-TCP) biomaterial in anterior spine fusion in a pig model.

"PRP is an autogenous source of growth factor and has been shown to enhance bone healing both in clinical and experimental studies. PRP in combination with porous hydroxyapatite has been shown to increase the bone ingrowth in a bone chamber rat model," scientists in Denmark report.

"The present study investigated whether the combination of beta-TCP and PRP may enhance spinal fusion in a controlled animal study. Ten Danish Landrace pigs were used as a...


Source: Disease Risk Factor Week (2004-10-17)

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