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Albert Einstein College of Medicine
Parasite gene is a master of antimalarial resistance
October 17th, 2004
A malaria parasite gene called pfcrt, already confirmed as the culprit behind resistance to the drug chloroquine in the malaria species Plasmodium falciparum, may be responsible for resistance to several other antimalarial drugs as well, a team of researchers reports. The discovery of pfcrt's "central role" in malarial drug resistance could "help in the development of new therapeutic strategies that are effective against chloroquine-resistant parasites," said David Fidock of Albert Einstein College of Medicine, one of the lead authors of the paper. Nearly 3 million people, mostly children, die from malaria each year. Chloroquine is one of the...
Source: Disease Risk Factor Week (2004-10-17)
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