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Disease Risk Factor Week

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Baylor College of Medicine



Monocyte behavior in HIV-1 influenced by FNf and protease/antiprotease ratio



October 17th, 2004

FNf and protease and antiprotease ratio influence monocyte behavior in HIV-1 infection.

"To identify signals that can alter leukocyte function in patients receiving highly active antiretroviral therapy (HAART), we analyzed single blood samples from 74 HIV-1-infected patients and additional blood was collected at 90-day intervals from 51 HIV-1-infected patients over a 516±172 (mean±Sb) day interval," scientists writing in the Journal of Immunology report.

"Despite the absence of circulating immune complexes and normalization of phagocytic function compared with controls, the fraction of patients' monocytes expressing CD49e and...


Source: Disease Risk Factor Week (2004-10-17)

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