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Disease Risk Factor Week

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Boston University



Increased pulse pressure may explain relation of CVD to systolic blood pressure



October 17th, 2004

Recent research has offered a likely explanation for the J-curve of blood pressure cardiovascular risk.

Researchers in the United States report, "We prospectively tested in the combined original and offspring Framingham cohorts the hypothesis that the increase in cardiovascular disease (CVD) incidence at low diastolic blood pressure (BP) is largely confined to subjects with increased systolic BP and hence an increased pulse pressure."

W.B. Kannel and colleagues of Boston University wrote, "The 10-year risk of 951 non-fatal CVD events and 204 CVD deaths was estimated at diastolic pressures of <80, 80 to 90, and {{>=}}90 mm Hg, according to...


Source: Disease Risk Factor Week (2004-10-17)

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